Decomposition of Pharmaceuticals
Thermal analysis is a common characterization technique used in the manufacturing and testing of pharmaceutical drugs. TGA is a common methodology to examine the excipients that are used pharma manufacturing. It is vital to know how the active ingredients in the drug will thermally behave with the numerous excipients when combined. TGA can provide data based on the decomposition or decomposition’s at various temperatures. Pharma products can be manufactured using hot melt extrusion techniques which all the components are exposed to elevated temperatures. It is require information to ensure that all the components have excellent thermal stability.
Application based Polymer Testing
There are numerous polymers that are used in everyday life covering a wide berth of applications. Polymers themselves are long chains of molecules and the they behave differently based on the linkage of the molecules and the conditions that they are formed, primarily pressure and temperatures. DSC provides a large amount of data on how a polymer can perform based on its thermal data. Polymers that are exposed to increased temperatures require high melting points. When a known or unknown polymer is tested using DSC the following information can be revealed:
- Glass transition temperature
- Crystallization point
- Melting point
- Heat capacity